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EDC-HCl zero-length crosslinker (EDAC-HCl, EDC or EDAC; EDCI; 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride) from ProteoChem is ultrapure, and is used to conjugate carboxyl functional groups to primary amines as found in peptides and proteins. It is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticals. The convenient 10 mg packaging is great for using ProteoChem's EDC-HCl in Luminex bead conjugation reactions. EDC-HCl is water soluble, thus the reaction can take place at physiological conditions; although the best results take place at pH of 5.5 or less buffered in MES. Sulfo-NHS or NHS is used as a catalyst for EDC-HCl coupling and greatly increases the efficiency of the reaction.
CAS Number: 25952-53-8
Purity: ≥ 99%
Visual: White powder
Melting Point: 110-114ēC
Click here for: EDC-HCl Product Information Sheet & General Protocol
Chemical Formula: C8H17N3 ˇ HCl
Molecular Weight: 191.7
EC Number: 247-361-2
Beilstein Registry Number: 5764110
MDL number: MFCD00012503
PubChem Substance ID: 24894654
Alternative Names: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide HCl; N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; EDAC.HCl; EDC.HCl; EDCI
Bastarrachea, L. J., Peleg, M., McLandsborough, L. A., & Goddard, J. M. (2013). Inactivation of< i> Listeria monocytogenes on a polyethylene surface modified by layer-by-layer deposition of the antimicrobial N-halamine. Journal of Food Engineering.
Bastarrachea, L. J., & Goddard, J. M. (2013). Development of antimicrobial stainless steel via surface modification with N‐halamines: Characterization of surface chemistry and N‐halamine chlorination. Journal of Applied Polymer Science, 127(1), 821-831.
Special bulk pricing is available on bulk quantities of EDC-HCl for your large volume manufacturing application.