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Proteochem's ultrapure, zero-length crosslinker 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl or EDAC-HCl) is used to conjugate carboxyl functional groups to primary amines as found in peptides and proteins. It is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticals. EDC-HCl is water soluble, thus the reaction can take place at physiological conditions; although the best results take place at pH of 5.5 or less buffered in MES. Sulfo-NHS or NHS is used as a catalyst for EDC-HCl coupling and greatly increases the efficiency of the reaction.
CAS Number: 25952-53-8
Purity: ≥ 99%
Visual: White powder
Melting Point: 110-114ēC
Click here for: EDC-HCl Product Information Sheet & General Protocol
Chemical Formula: C8H17N3 ˇ HCl
Molecular Weight: 191.7
EC Number: 247-361-2
Beilstein Registry Number: 5764110
MDL number: MFCD00012503
PubChem Substance ID: 24894654
Alternative Names: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide HCl; N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; EDAC.HCl; EDC.HCl
Special bulk pricing is available on bulk quantities of EDC for your large volume manufacturing application.