PDPH Crosslinking Reagent 1 gram - 3-(2-Pyridyldithio)propionyl hydrazide (PDPH) -       
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PDPH Crosslinker 1 gram
[c1113-1gm]

$1,247.00

PDPH Crosslinking Reagent Structure, 3-(2-Pyridyldithio)propionyl hydrazide

3-(2-Pyridyldithio)propionyl hydrazide (PDPH crosslinking reagent) is a cleavable, heterobifunctional protein crosslinker. PDPH crosslinking reagent's hydrazide group selectively reacts with oxidized carbohydrates (or carboxyls when used with EDC); while the pyridinyldisulfide moity is reactive toward reduced thiols (sulfhydryls; -SH). Thus, PDPH linker is an excellent choice for crosslinking glycoproteins and other polysaccharides.

Additionally, PDPH crosslinking reagent's pyridyldisulfide group contains a cleavable disulfide (-S-S-) bond which exposes a thiol moity that can be further reacted with, for example, a maleimide containing crosslinker.

PDPH is soluble at 14.2 mg/mL in pH 5.5 0.1 M Sodium Acetate.

Molecular Weight: 229.32

Spacer Length: 9.2

Special bulk pricing is available on bulk quantities of PDPH crosslinking reagent for your large volume manufacturing application.

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