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Homobifunctional Crosslinkers

Homobifunctional Crosslinkers

Homobifunctional crosslinkers possess identical reactive groups at opposite ends of the crosslinker’s spacer arm. Homobifunctional protein crosslinkers have the advantage of being reacted in a one-step chemical crosslinking reaction. Homobifunctional crosslinkers can be used in the formation of protein dimers and protein polymers while crosslinking proteins.

Homobifunctional Crosslinker Selection Guide
Crosslinker
Acronym
Spacer Arm
Length
M.W. Reactivity Cleavable
By
Membrane
Permeable
Water
Soluble
BS2G 7.7 Å 530.4 -NH2 ; -NH2 - No Yes
BS3 11.4 Å 572.4 -NH2 ; -NH2 - No Yes
DSG 7.7 Å 326.3 -NH2 ; -NH2 - Yes No
DSP 12.0 Å 404.4 -NH2 ; -NH2 Thiols Yes No
DSS 11.4 Å 368.3 -NH2 ; -NH2 - Yes No
DSSeb 14.1 Å 396.4 -NH2 ; -NH2 - Yes No
DST 6.4 Å 344.2 -NH2 ; -NH2 Periodate Yes Yes
DTSSP 12.0 Å 608.5 -NH2 ; -NH2 Thiols No Yes
EGS 16.1 Å 456.4 -NH2 ; -NH2 Hydroxylamine Yes No
Sulfo-EGS 16.1 Å 660.5 -NH2 ; -NH2 Hydroxylamine No Yes

Please follow the links below to see pricing and product information:

BS3
BS3
DSS
DSS
BS2G
BS2G
DSG
DSG
DSP
DSP
DTSSP
DTSSP
Sulfo-EGS
Sulfo-EGS
EGS
EGS
DST
DST
DSSeb
DSSeb

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