SPDP Crosslinking Reagent 1 gram bulk - N-Succinimidyl 3-(2-pyridyldithio)-propionate (SPDP) -       
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SPDP Crosslinker 1 gram
[c1116-1gm]

$1,055.00

N-Succinimidyl 3-(2-pyridyldithio)-propionate, SPDP Crosslinking Reagent Structure, CAS # 68181-17-9

N-Succinimidyl 3-(2-pyridyldithio)-propionate (SPDP crosslinking reagent) is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional crosslinker. SPDP crosslinking reagent's reactive moites consist of an N-hydroxysuccinimide (NHS) ester that reacts with primary amines, as found in lysine side chains. On the other end of the SPDP crosslinking molecule pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond.

ProteoChem also offers a "long chain" version of SPDP crosslinking reagent. LC-SPDP has a 15.7 angstrom spacer arm, compared to the shorter 6.8 angstrom spacer arm version of SPDP crosslinking reagent. Often, due to steric hindrances, it is desirable to empirically test which of the two versions will work best in your specific application.

Click here for: SPDP Crosslinking Reagent Product Information Sheet & General Protocol

Molecular Weight: 312.4

Spacer Length: 6.8

CAS Number: 68181-17-9

Alternative Name: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester

Special bulk pricing is available on bulk quantities of SPDP crosslinking reagent for your large volume manufacturing application.

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Currently viewing:  SPDP Crosslinking Reagent 1 gram bulk - N-Succinimidyl 3-(2-pyridyldithio)-propionate (SPDP) - ProteoChem
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