Traut's Reagent (2-Iminothiolane HCl) is commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation. Traut's Reagent is water soluble. This protein modification reagent is amino reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides. In addition, Traut's Reagent is a useful RNA-protein crosslinking reagent.
Molecular Weight: 137.63
Spacer Length: 8.1 Å
CAS Number: 4781-83-3
Alternative Names: 2-Iminothiolane HCl; 2-Iminothiolane hydrochloride; 2-Iminothiolane; 2-IT; Trauts reagent
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