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LCMS Acetonitrile 1 L


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Applications for LCMS Acetonitrile
LCMS grade Acetonitrile (ACN) solvent from ProteoChem is well suited for both reverse and normal phase LCMS applications. LCMS Acetonitrile is an ideal mobile phase solvent for separation of peptides or proteins in reverse phase liquid chromatography and mass spectrometry (HPLC-MS). ProteoChem's LCMS Acetonitrile purity is ≥ 99.9% to allow maximum sensitivity of your assay.

All of ProteoChem's LCMS solvents are lot tested to ensure minimized levels of signal suppressing contaminants and low evaporative residue levels. ProteoChem's LCMS Acetonitrile also allows for high sensitivity detection at a wide range of UV detection wavelengths, including the low UV wavelengths, where many other solvent brands contain interferents. Each lot of ProteoChem's LCMS grade Acetonitrile is tested to ensure suitability in LCMS and HPLC functions, making this product an ideal choice for instruments that perform both chromatography and mass spectrometry.

ProteoChem also offers an exceptionally high purity HPLC grade Acetonitrile.

Molecular Formula: C2H3N

Molecular Weight: 41.05

Density: 0.786 g/mL

CAS Number: 75-05-8

Alternative Names: Methyl cyanide; Cyanomethane; Ethanenitrile; LC-MS Acetonitrile; LC/MS Acetonitrile, LC/MS ACN, LCMS ACN, MS grade Acetonitrile

LCMS Acetonitrile Specifications
ProteoChem's LCMS Acetonitrile is manufactured to the highest specifications to ensure the integrity of your data, maximize sensitivity in your assay and to prolong the life of your equipment. With ProteoChem's LCMS Grade Solvents, scientists can expect a consistent, high purity product which is necessary to create reliable chromatography methods and protocols. LCMS Acetonitrile is tested to meet the following specifications:

Assay (by GC)
≥ 99.9%
Residue after Evaporation
≤ 0.8 ppm
≤ 0.01%
LC Gradient Suitability at 254 and 210 nm
Passes Test
Titratable acid, mEQ/g
≤ 0.008
Titratable base, mEQ/g
≤ 0.0006
LCMS Gradient Suitability
Passes Test
LCMS at Positive Mode as Reserpine
≤ 50 ppb
LCMS at Negative Mode as Aldicarb
≤ 50 ppb
Optical Absorbance at:
190 nm
≤ 1.00
195 nm
≤ 0.15
200 nm
≤ 0.05
205 nm
≤ 0.04
210 nm
≤ 0.03
215 nm
≤ 0.025
220 nm
≤ 0.015
225 nm
≤ 0.015
230 nm
≤ 0.01
254 nm
≤ 0.005
280 nm
≤ 0.005
Aluminum (Al)
≤ 25 ppb
Barium (Ba)
≤ 5 ppb
Cadmium (Cd)
≤ 5 ppb
Calcium (Ca)
≤ 25 ppb
Chromium (Cr)
≤ 5 ppb
Cobalt (Co)
≤ 5 ppb
Copper (Cu)
≤ 5 ppb
Iron (Fe)
≤ 5 ppb
Lead (Pb)
≤ 5 ppb
Magnesium (Mg)
≤ 10 ppb
Nickel (Ni)
≤ 5 ppb
Potassium (K)
≤ 10 ppb
Silver (Ag)
≤ 5 ppb
Sodium (Na)
≤ 50 ppb
Tin (Sn)
≤ 5 ppb
Zinc (Zn)
≤ 10 ppb

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