GMBS crosslinker (N-[Gamma-Maleimidobutyryloxy] Succinimide) is a non-cleavable, water insoluble, heterobifunctional protein crosslinker. The GMBS crosslinking reagent is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The GMBS protein crosslinker has a short spacer arm length of 7.3 angstroms and is less immunogenic than the analogous MBS crosslinker. The GMBS crosslinker's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.
Molecular Weight: 280.23
Spacer Length: 7.3 Å
CAS Number: 80307-12-6
Alternative Name: 4-Maleimdobutyric acid N-succinimidyl ester; N-γ-maleimidobutyryl-oxysuccinimide ester; N-(γ-Maleimidobutyryloxy)succinimide; N-Succinimidyl 4-maleimidobutyrate
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