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N-hydroxysulfosuccinimide (Sulfo-NHS) is used in conjunction with EDC-HCl (EDAC-HCl) to convert carboxyl groups to Sulfo-NHS esters which react with primary amines. Sulfo-NHS is used as the catalyst for EDC-HCl coupling and greatly increases the efficiency of the reaction. Sulfo-NHS is ideal for covalently binding protein or peptides to carboxyl containing beads, resins, or other nanoparticals. Sulfo-NHS is water soluble, thus the reaction can take place at physiological conditions.
Click here for: Sulfo-NHS Product Information Sheet & General Protocol
CAS Number: 106627-54-7
Molecular Weight: 217.13
Alternative Name: N-Hydroxysulfosuccinimide sodium salt; Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid
Special bulk pricing is available on bulk quantities of Sulfo-NHS for your large volume manufacturing application.